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Scientific programme


The 2-day scientific part consists of 17 oral presentations and includes a poster session. At the accompanying exhibition companies from the biotechnological and related industries will present the latest innovations in biotechnology and the most advanced tools currently available on the market.

Unless otherwise stated, oral presentations will last 30 minutes with a subsequent 10 minutes for discussion. For posters, in an A0 format (900 x 1250 mm), a limited number of panels will be placed in the foyer close to the industry exhibition. Each section will finish with a panel discussion.

The following speakers (in alphabetical order) have already agreed to give presentations at BioTech 2008:

Prof. Dr. Markus Aebi, Swiss Federal Institute of Technology, Zurich CH
N-linked protein glycosylation in yeast
(post-translational modification in the ER and the potential use in biotechnology)

Dr. Pavla Bojarová, Institute of Microbiology ASCR, Prague CZ

Modified substrates in enzymatic glycosylations: a simple route to complex saccharides
(Aspergillus, glycosidase, modified glycosyl donor, molecular modelling, Penicillium, Talaromyces, transglycosylation)

Dr. Adriana Botes, Oxyrane UK Ltd, Manchester UK
Yarrowia lipolytica: a versatile expression system for the production of biopharmaceuticals

(yeast, glycosylation, secretion, surface display, regulatable promoters, mating type switching, unfolded protein response, membrane proteins)

PD Dr. Matthias Bureik, PomBioTech GmbH, Saarbrücken D
Production of cytochrome P450-metabolites using recombinant fission yeast Schizosaccharomyces pombe
(production of drug metabolites, steroid hydroxylation, P450 inhibitor assays, electron transfer chains, metabolic flux analysis)

Prof. Dr. James M. Cregg, Keck Graduate Institute of Applied Life Sciences, Claremont USA
Genomics comes to the recombinant protein production yeast Pichia pastoris

Prof. Dr. Nico Callewaert, Flanders Institute for Biotechnology vzw, Ghent B
Secretory system engineered yeast expression systems: taking the prototypes further
(Pichia pastoris, dimorphic yeasts, glycosylation, folding, cytokines)

Dr. Brigitte Gasser, BOKU-University of Natural Resources and Applied Life Sciences, Vienna A
Physiological characterisation and strain engineering of Pichia pastoris by transcriptomics and proteomics
(genome annotation, microarray development, and the application of -omics to analyze cellular responses to protein overexpression and fermentation conditions, and the identification of secretion enhancers)

Prof. Dr. Gerd Gellissen, PharmedArtis GmbH, Forckenbeckstr. 6, Aachen D
Strain design and its impact on process development in H. polymorpha and other yeasts

Prof. Dr. Oreste Ghisalba, Novartis Pharma AG, Basel CH
Enzymatic synthesis of glycoconjugates
(activated carbohydrates, glycosyltraspherases, possibilities of in vitro approaches)

Dr. Carmen Jungo, Lonza Ltd, Visp CH
Alternative cultivation strategies with Pichia pastoris for the production of therapeutic recombinant proteins
(induction with mixed substrates and expression with GAP promoter)

Dr. Pavel Kyslík, Institute of Microbiology ASCR, Prague CZ
Intracellular expression of heterologous gene encoding bacterial penicillin acylase in Pichia pastoris
(Pichia pastoris, penicillin acylase, intracellular proenzyme processing, enzyme authenticity)

Prof. Dr. Christine Lang, TU Berlin D
A comparative view on yeast expression hosts S. cerevisiae and P. pastoris
(high throughput expression systems, key factors determining expression level, structural genomics)

Dr. Michael Piontek, ARTES Biotechnology GmbH, Langenfeld D
Co-expression of homologous and heterologous genes as tools for advancement of established and new yeast expression systems
(Hansenula polymorpha, Arxula adeninivorans, secretion, chaperone, biotransformation)

Dr. Peter J. Punt, TNO, AJ Zeist NL
Fungal cell factories: production and screening of antibody (-fragments)
(comparison filamentous and unicellular fungi, Aspergillus, Chrysosporium, antibody, scFv, Vhh, protease mutants, HTS screening, N-glycosylation)

Prof. Dr. Jack Rohrer, University of Zurich, CH
Test for carbohydrate specific internalisation of biosimilars

Claudia Ruth, Institute of Molecular Biotechnology, TU Graz A
Methanol free protein expression by Pichia pastoris using methanol inducible promoter variants
(reducing cellular stress and toxicity problems by tunable protein expression and high level protein expression while avoiding methanol for induction and cell growth)

Dr. Ralf Thoma, F. Hoffmann-La Roche AG, Basel CH
Pichia pastoris: a powerful expression system to support drug discovery projects in pharmaceutical industry
(expression optimisation, membrane proteins, deglycosylation, X-ray structures)

Picture gallery

Conference proceedings
Download proceedings (ISBN 978-3-905745-14-6) here!

Arrival to Wädenswil


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